Researchers discover that Aspirin use may reduce risk of cancer
Recently, researchers discovered that aspirin use is correlated with a significantly reduced risk of developing bile duct cancer, also known as cholangiocarcinoma.
Senior author Lewis Roberts stated that their study found that individuals who took aspirin had a more than a two-and-a-half to three-and-a-half-fold lower chance of developing bile duct cancer, compared to people who did not take aspirin.
Bile duct cancer is an unusual cancer that forms in the slender tubes that carry digestive fluid through the liver. The disease appears mainly in individuals over 50 and can cause symptoms, like yellowing of the skin and eyes, excessive itchiness of the skin. Bile duct cancer is an intense type of cancer that evolutes quickly and is very difficult to treat.
Aspirin has anti-inflammatory characteristics, which may reduce the risk of bile duct cancer by lowering inflammation through inhibition of an enzyme known as cyclo-oxygenase (COX).
In addition to the COX enzyme pathway, Dr. Roberts stated other studies have shown that aspirin blocks additional cell-signaling cascades that promote cancer development.
But, it is not sure that aspirin is safe to use to prevent cancer.
Dr. Roberts stated that additional confirmatory studies are needed before aspirin can be suggested for use in preventing bile duct cancer.
This study appears in the journal Hepatology.